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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
19.39
Human Site:
Y725
Identified Species:
35.56
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
Y725
F
E
D
G
D
I
K
Y
I
F
T
A
N
K
K
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
Q705
A
I
A
S
D
A
E
Q
E
P
K
I
D
P
Y
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
Y725
F
E
D
G
D
I
K
Y
I
F
T
A
N
K
K
Dog
Lupus familis
XP_534693
2280
250152
Y794
F
E
D
G
D
I
K
Y
I
F
T
A
N
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
Y720
F
E
D
G
D
I
K
Y
I
F
T
A
N
K
K
Rat
Rattus norvegicus
NP_001101807
1374
149708
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
Q687
A
V
V
S
D
A
E
Q
E
P
E
I
D
P
Y
Chicken
Gallus gallus
XP_415317
2195
241321
Y702
F
E
D
G
D
I
K
Y
S
F
T
G
N
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
V640
F
H
T
P
H
L
P
V
V
A
H
F
E
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
T920
F
Q
G
L
N
I
K
T
E
P
G
L
H
S
P
Honey Bee
Apis mellifera
XP_393643
1982
216109
P539
P
G
P
T
L
K
R
P
V
L
V
S
R
E
C
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
A1075
M
H
T
K
S
R
Y
A
M
N
T
L
E
D
D
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
6.6
86.6
N.A.
6.6
N.A.
20
0
6.6
0
P-Site Similarity:
100
20
100
100
N.A.
100
0
N.A.
20
86.6
N.A.
20
N.A.
40
26.6
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
16
0
8
0
8
0
31
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
39
0
54
0
0
0
0
0
0
0
16
16
8
% D
% Glu:
0
39
0
0
0
0
16
0
24
0
8
0
16
8
0
% E
% Phe:
54
0
0
0
0
0
0
0
0
39
0
8
0
0
0
% F
% Gly:
0
8
8
39
0
0
0
0
0
0
8
8
0
0
8
% G
% His:
0
16
0
0
8
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
8
0
0
0
47
0
0
31
0
0
16
0
0
0
% I
% Lys:
0
0
0
8
0
8
47
0
0
0
8
0
0
39
39
% K
% Leu:
0
0
0
8
8
8
0
0
0
8
0
16
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
0
0
39
0
0
% N
% Pro:
8
0
8
8
0
0
8
8
0
24
0
0
0
16
8
% P
% Gln:
0
8
0
0
0
0
0
16
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
16
8
0
0
0
8
0
0
8
0
8
0
% S
% Thr:
0
0
16
8
0
0
0
8
0
0
47
0
0
0
0
% T
% Val:
0
8
8
0
0
0
0
8
16
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
39
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _